The Amerisleep AS2 Mattress is a top choice for those with scoliosis and sciatica, thanks to its unique combination of comfort and support. This medium-firm mattress is designed to provide the perfect balance of cushioning and firmness, making it ideal for relieving pressure points and promoting proper spinal alignment. With its advanced foam layers and innovative design, the Amerisleep AS2 is consistently ranked as one of the best mattresses for those with back pain.1. Amerisleep AS2 Mattress
The Helix Midnight Mattress is a hybrid mattress that is specifically designed to provide targeted support for those with scoliosis and sciatica. It features a combination of memory foam and pocketed coils, which work together to contour to the body and provide pressure relief. The Helix Midnight also has a medium-firm feel, making it a great option for those who need extra support for their back while still enjoying a comfortable night's sleep.2. Helix Midnight Mattress
The Saatva Classic Mattress is a luxurious innerspring mattress that offers exceptional support and comfort. Its unique dual-coil system provides both the necessary support for those with back pain and the cushioning needed for a good night's rest. The Saatva Classic also has a euro pillow top for added comfort, making it an excellent choice for those with scoliosis and sciatica.3. Saatva Classic Mattress
The Purple Hybrid Premier Mattress is a top-rated option for those with back pain. Its innovative Purple Grid technology provides targeted pressure relief, while its responsive pocketed coils offer optimal support. The Purple Hybrid Premier also has a medium-firm feel, making it a great choice for those who need both comfort and support for their back.4. Purple Hybrid Premier Mattress
The Nectar Memory Foam Mattress is designed with a combination of memory foam and high-density foam to provide superior support and comfort. Its adaptive foam layers contour to the body, relieving pressure points and promoting proper spinal alignment. The Nectar mattress also comes with a 365-night sleep trial and a lifetime warranty, making it a risk-free investment for those with scoliosis and sciatica.5. Nectar Memory Foam Mattress
The Layla Hybrid Mattress is a unique option for those with back pain, as it features a flippable design with both a soft and a firm side. This allows sleepers to choose the level of firmness that works best for their individual needs. The Layla Hybrid also features copper-infused memory foam, which provides both comfort and targeted support for pressure points.6. Layla Hybrid Mattress
The Casper Wave Hybrid Mattress is designed with advanced technology to provide targeted support and pressure relief for those with back pain. Its zoned support system and gel-infused memory foam work together to properly align the spine and relieve pressure points. The Casper Wave Hybrid also has a medium-firm feel, making it a great choice for those who need extra support for their back.7. Casper Wave Hybrid Mattress
The Leesa Hybrid Mattress is a hybrid option that combines memory foam and pocketed coils to provide the perfect blend of comfort and support. Its top layer of foam is designed to relieve pressure points, while its pocketed coils provide targeted support for the spine. The Leesa Hybrid also has a medium-firm feel, making it a great choice for those with back pain.8. Leesa Hybrid Mattress
The Tempur-Pedic ProAdapt Mattress is a top-performing option for those with back pain. Its advanced Tempur materials provide superior support and contouring, while its SmartClimate Dual Cover system keeps the mattress cool and comfortable. The Tempur-Pedic ProAdapt also comes in multiple firmness options, making it suitable for a wide range of sleep preferences.9. Tempur-Pedic ProAdapt Mattress
The Tuft & Needle Mint Mattress is designed with a unique adaptive foam that provides both comfort and support for those with back pain. Its open-cell structure allows for optimal breathability, and its graphite and gel infusions help to regulate body temperature. The Tuft & Needle Mint also has a medium-firm feel, making it a great choice for those who need extra support for their back.10. Tuft & Needle Mint Mattress